In order to study the deployment process of missile folded wings in flying environment, The CFD software CFD-FASTRAN was used for simulating it, including problem description, mesh generation and calculation parameter setup etc. According to calculation result, the synchronization and angular velocity of four folded wings as well as missile attitude and angular velocity during deployment process were given. The results show that the simulation method is feasible, the calculation result could offer reference basis for the missile about overall design, trajectory design and wing structural design etc.