In order to solve some problems on single function, bad human-computer interaction and difficult integrating of general interior ballistic software, the mixed programming technology of C# and MATLAB was applied to develop an interior ballistic design computation software for the simple shape of powders, multi-perforated propellants, mixed charge and deterred grain based on classical interior ballistic model, which can be developed and integrated with the modules based on improved and two-phase flow interior ballistics. While the mixed programming technology can also be applied to popularize in artillery design computations, such as external ballistics, gun barrel and recoil system etc., which has good commonality and expansibility.