Lateral jet interaction for oblique jet powered missile was simulated numerically by solving N-S equations. Through investigating shocks and vortices structure of lateral jet interaction flowfield and oblique jet powered flowfield effects of angle of attack and Mach number on lateral jet flowfield structure and surface pressure coefficient distribution were analyzed, and variation feature of lateral jet interaction effect was studied, the results indicate that jet force is reduced by interaction force when lateral jet at windward side and is amplified when interaction force at leeward side at higher angle of attack, while jet moment is amplified by interaction moment when lateral jet both at windward side and at leeward side.