Through the study on the problem that the tracking point is inconsistent when handover for IR/microwave seeker, the reasons for that were analyzed. Focused on this problem, the adaptive guidance of microwave phase interferometer was researched, the guidance law which modifies the offset was derived and simplified, and the implementation scheme was given. The handover simulation was done considering that the inconsistent tracking point problem. The conclusion is that the tracking point inconsistent problem has influence on trajectory when handover. After using adaptive guidance, the trajectory parametric curve oscillates dra-matically at the end and more overload is needed, which shows effectiveness of the adaptive guidance.