A type of guideway target missile was launched by inclined thermal emission on the launcher. The target missile moved alone the guideway direction, which depended on the slider.After the front slider of the target missile left the guideway, the projectile body will rotate around the rear slider due to gravity, which caused the head of target missile to sink, resulting in the risk of collision between the target missile and the guideway. In order to analyze the safety of target missile during launching process.The trajectory program and the initial value were set, and the flight state and parameters of the target missile at each time were obtained through integral calculation. Through ADAMS software simulation, the relevant data affecting its launch safety were obtained. Different launch conditions of motion parameters analyzed when target missile was launched on Launcher. In order to verify the correctness of theoretical arithmetic and ADAMS software simulation data, the launching test was carried out with launching angle of 60 degree and guideway length of 9 m, the relevant data of the launch process were obtained. Through the analysis of test data, the correctness of trajectory calculation and simulation results was proved, it provided a design basis for the launch safety design security of target missile.