In order to study the aerodynamic characteristics of the cruciform tail missile model, the three-dimensional modeling of the missile is carried out by three-dimensional modeling software. The three-dimensional model is meshed by the grid partitioning software. The aerodynamic characteristics of the missile model are analyzed by using the Spalart-Allmaras turbulence mode. The numerical simulation is used to study the flow condition circumstance of air around the missile model, and the regular patterns of aerodynamics, moment, drag coefficient and lift coefficient of missiles in different Mach numbers and different angles of attack are analyzed. The results of the study are of great significance to the aerodynamic design of the missile with cross-shaped tail and the subsequent design of the flight control system.