To investigate effect of velocity magnitude V, equivalence ratio of air and fuel φ, temperature at inlet T on the performance of three-dimensional annular Trapped Vortex Combustor (TVC) with flow guide vanes, the effect of different gas parameters at the inlet on velocity, vortex structure, NO emission distribution, total pressure loss coefficient σ, combustion efficiency η were numerically analysized. The results show that the vortex structure, the NO distribution and η at the outlet are almost unchanged with the increase of V, but σ increases rapidly with the increase of V; The increase of T is beneficial to trapping vortexes in the cavity, reducing σ and increasing η; when φ and T become larger, the temperature in the TVC and the NO emission at the outlet increase significantly.