In order to examine the wounding effect of airbag kinetic energy ammunition, firstly, the control volume method was used to make the simulation analysis of static airbag inflation process. The simulation result demonstrated that the airbag system could finish the inflation within 10 ms, so as to form the ellipsoid airbag which half axle lenghes were 60 mm, 60 mm and 50 mm respectively. Secondly, the ANSYS/LS-DYNA software was utilized to make a dynamic simulation analysis of wounding effect caused by airbag kinetic energy ammunition with 70 m/s, 80 m/s and 90 m/s initial velocity respectively. Then the striking effect diagram and the stress distribution nephogram of airbag kinetic energy ammunition were obtained. The simulation result demonstrated that the airbag kinetic energy ammunition possessesd favorable non-lethal effect and strike effect under the condition of the speed of 80 m/s.