The problem that air defense missile kills the target in the full area and complicated encounter can be solved by adaptive detonation delay control technique. In the article, the optimal detonation delay time model was built Take a certain air defense missile as an example, the simulation of the Monte Carlo statistical test was carried out, the factor impacting the adaptive detonation delay control was analyzed, two methods of auto adjusting detonation delay control were put forward. The simulation results demonstrate the method is logical and feasible.