Mo-Cu superfine powder was prepared by mechanical alloying process, and then the powder was sintered by selective laser melting. The optimal parameters were obtained, that is, 270W laser power, 2000mm/min in the scanning velocity, 0.2mm in powder depth. Mo-Cu Missile engine nozzle was produced by the optimal parameter. After the high temperature sintering, the mechanical property of Mo-Cu engine nozzle was measured. The results showed the tensile strength and elongation of Mo-Cu part reach 550 MPa, and 7.3%, respectively. It's comprehensive property is better than that of Mo nozzle, which can meet development of new type products.