Laser fuse is an important part of modern laser homing system.In the traditional fuze circuit design,many fuze circuits were designed by using a variety of small and middle scale integrated circuit chips and microcontrollers.The laser fuze circuit was designed by a piece of FPGA,which makes laser fuze have more accuracy and intelligence by making use of FPGA hardware source design controlling circuit and signal processing module.The fuze circuit based on FPGA was simulated by software tools and debugged with hardware.It was proved that the fuze circuit based on FPGA can improve precision and increase circuit’s feasibility.