Aiming at the problems in simulating and calculating attack area of air-to-air missile, a simple and convenient method for simulating and calculating attack area of air-to-air missile was provided. Firstly, missile trajectory simulation model was established according to modular design method, including target motion module, missile motion module, relative motion module, missile guidance module and hitting conditions restriction module; Secondly, a script file was established and Matlab programme was used for setting simulation parameters, changing approaching angle and calculating the distance between missile and target according to dichotomy, then missile trajectory simulation model was transferred. Lastly, the correctness of the missile trajectory simulation model and the feasibility of the calculation of attack area were proved through simulation.