In view of twice-detonating fuze delay time occurred in static explosive experiment of FAE, the anti-interference methods including improving voltage stabilizing circuit reliability, increasing cable cutting off function and optimization of circuit board wiring design, etc, were used for improving anti-interference ability of twice-detonating fuze. Through delay time of fuze and static explosive experiment of FAE, the results show that anti-interference method is effective on restraining interference from first-detonating shock, fuel and detonation products, and solves the problem of time deviation. Time delay fuze is accurate, anti-interference methods are effective, these improves reliability of detonating fuze.