To explore under explosion loading solidliquidsolid interlayer response characteristics of the structure, the numerical simulation method, with solidliquidsolid insulation layer of the structure of the working condition of variable crosssection tube, based on the eulerLagrange coupling method to establish the explosion shock wavelaminar flow and solid coupling model, the explosion shock wave in solidliquidsolid is used to numerically simulate the transmission characteristics of interlayer structure. The response process of solidliquidsolid interlayer structure under the impact of explosion is analyzed. On this basis, the effects of the length of liquid interlayer and the brittleness of solid interlayer on the fracture characteristics of interlayer are emphatically explored. The research results show that the solidliquidsolid insulation layer structure of crushing process is mainly composed of solid interlayer deformation stages, liquid barrier before storming phase and solid barrier block after stage of three parts, the deformation of solid insulation layer and the liquid shock wave propagation is affect the solidliquidsolid insulation layer structure, the main factors and as a result of the backend solid barrier block effect, in the spread of the liquid in the interlayer stress wave reflection rarefaction wave formation, the explosion airflow movement in the opposite direction of jet flow phenomenon center.