In order to evaluate the missile damage effectiveness under the combat circumstance, the deficiency of accumulative killing probability model is analyzed. The influence of the screen strip jamming on guiding capability and exploding probability is considered. The quadratic damage to aircraft vulnerability which is based on multiple hit was studied. The nonlinear model which was equal to damage result changing with time was introduced. The computing model was established which was based on jamming and quadratic damage effect. The validity of the model is validated by simulated. A significative theory reference is supplied to evaluate the missile damage effectiveness under actual combat surrounding.